Dosage :
It’s often prescribed in a short term course, typically five day. It’s important to take the full prescribed dose even if symptoms improve to ensure the infection is complete treated. Oral use – Throat Infection, Respiratory Tract Infections and skin infections Active immunisation against typhoid fever caused by Salmononella Typhi Consult a healthcare professional for personalised advice and information.COMMON SIDE EFFECTS :
- Feeling Sick OR Nausea
- Loss of appetite
- Headache
- Diarrhoea
- Irritation, Itching
- Dry mouth
Mechanism of Action :
Bacteria need a certain method of protein synthesis, made by ribosomal proteins in order to multiply. Azithromycin attaches itself to the bacterial 505 ribosomal sub units 23s rRNA. By blocking the transpeptidation/ translocation stage of protein synthesis and the construction of the 505 ribosomal sub unit, it prevent the production of proteins in bacteria. As a result several bacterial infections are controlled. The broad spectrum antibacterial actions of macrolides, such as azithromycin 500 are in line with their great affinity for bacterial ribosoms. Compared to erythromycin ,azithromycin has a longer serum half life and is more concentrated in tissues because of its strong stability at low PH. Absoption : After oral dosing, azithromycin has a 37% bio-availability food has no effect on absorption. It is thought that P-glycoprotein (ABCBI) efflux transported which are known to be encoded by the ABCBI gene 4 mediate macrolide absorption in the intestine. Distribution : Following oral treatment tissues have range distributions of azithromycin with an apparent steady. State volume of distribution of 31.1L/kg label. Azithromycin concentrations in tissues have been found to be significantly higher than those in plasma or serum label. Azithromycin uptake has been found to be especially high in tonsils, prostrate and lung. Protein Binding : The serum protein binding of azithromycin varies in humans decreasing from 51% at 0.02g/ml to 7% at 2 g/ml Metabolism : Liver Excretion : This antibiotic is excreted by the bile duct, Kidney.What happens if I miss a dose?
The missed dose should be taken as soon as you remember. If your next planned dose is near, skip the missed dose. Never take additional medication to make up for a missing dosage.Drug Interaction :
Inform your physician of all the medications you take now, as well as any you begin or discontinue taking especially,- digoxin
- clarithromycin
- a blood thinner – warfarin, Coumadin, Jantoven, statins
- Antacid includes Aluminium or Magnesium
Precaution :
-
Do not take antacids 2 hours before or after taking Azithromycin. Antacid which contain Aluminium and Magnesium such as Gelusil, Digene, Milk of Magnesia,etc. These antacids can make azithromycin less effective when taken at the same time.
- Even if you feel better, make sure you complete the entire course of medication and don’t miss any doses. Early stopping may cause the infection to reappear and become more difficult to cure.
- When your treatment is over, diarrhea should stop, though it might happen as a side effect. If you notice blood in your stools or if it doesn’t stop, contact your doctor know about it.
FAQ for Azithromycin 500 :
Is Azithromycin an antibiotic ? Yes, Azithromycin is an antibiotic used to treat various bacterial infection. Is Azithromycin good for throat infection ? Azithromycin is used for various bacterial infection such as throat infection. Always consult your healthcare provider for better result. Should Azithromycin be taken before or with food ? Azithromycin is prescribed once daily. the medicine should be taken 1 hour before meals or 2 hours after eating food. you can take the azithromycin with or without food. Follow all the instructions exactly as advised by your doctor.Is Azithromycin 500 a strong antibiotic ?
Azithromycin is effective antibiotic used to treatment for several bacterial infections often involves. Azithromycin has a longer half-life than other antibiotics and remains in the body for a longer period of time, it is only administered once daily and for a short period of time. Azithromycin dose for throat infection for adults ? Dose of azithromycin for throat infection: Adults – 500 mg once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for 3 to 5 days. Always consult doctor for better result.